Antifungal Saponins from Paris polyphylla Smith

被引：103

作者：

Deng, Dawei ^{[1
]}

Lauren, Denis R. ^{[1
]}

Cooney, Janine M. ^{[1
]}

Jensen, Dwayne J. ^{[1
]}

Wurms, Kirstin V. ^{[1
]}

Upritchard, Jenine E. ^{[2
]}

Cannon, Richard D. ^{[2
]}

Wang, Ming Zhong ^{[3
]}

Li, Ming Zhang ^{[3
]}

机构：

[1] HortResearch, Ruakura Agr Res Ctr, Hamilton, New Zealand

[2] Univ Otago, Dept Oral Sci, Dunedin, New Zealand

[3] Sichuan Prov Nat Resources Res Inst, Chengdu, Sichuan, Peoples R China

来源：

PLANTA MEDICA | 2008年 / 74卷 / 11期

关键词：

saponins; pennogenin; Liliaceae; Paris polyphylla; antifungal activity;

D O I：

10.1055/s-2008-1081345

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Three steroidal saponins, including one new and two known compounds, were isolated from the rhizomes of Paris polyphylla Smith. One- and two-dimensional NMR, LC-MS, and interpretation of hydrolytic cleavage experiments led to the identification of the structure of the new saponin as (25R)-spirost-5-ene-3 beta,17 alpha-diol (pennogenin) 3-O-{O-alpha-L-rhamnopyranosyl-(1 -> 2)-O-[O-beta-xylopyranosyl-(1 -> 5)-alpha-L-arabinofuranosyl-(1 -> 4)]-beta-D-glucopyranoside}. The isolated saponins were evaluated for their antifungal activity against Cladosporium cladosporioides and Candida species and showed comparable activity to chemicals used in some commercial products.

引用

页码：1397 / 1402

页数：6

共 26 条

[1]

C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].

AGRAWAL, PK ;

JAIN, DC ;

GUPTA, RK ;

THAKUR, RS .

PHYTOCHEMISTRY, 1985, 24 (11) :2479-2496

[2]

CHEN C, 1983, YUNNAN ZHI WU YAN JI, V0005

[3]

CHEN CX, 1995, YUNNAN ZHIWU YANJIU, V17, P473

[4]

CHEN CX, 1981, YUNNAN ZHIWU YANJIU, V3, P89

[5]

A VERSATILE APPROACH FOR THE CONTROL OF FACTS EQUIPMENT IN MULTIMACHINE POWER-SYSTEMS [J].

CHEN, H ;

ANDERSSON, G .

INTERNATIONAL JOURNAL OF ELECTRICAL POWER & ENERGY SYSTEMS, 1995, 17 (03) :215-221

[6]

Silicon-mediated accumulation of flavonoid phytoalexins in cucumber [J].

Fawe, A ;

Abou-Zaid, M ;

Menzies, JG ;

Bélanger, RR .

PHYTOPATHOLOGY, 1998, 88 (05) :396-401

[7]

HUANG W-K, 1965, Yaoxue Xuebao, V12, P657

[8]

Liu Hai, 2006, Chinese Journal of Natural Medicines, V4, P264

[9]

STRUCTURE CHARACTERIZATION OF HEMOSTATIC DIOSGENIN GLYCOSIDES FROM PARIS-POLYPHYLIA [J].

MA, JCN ;

LAU, FW .

PHYTOCHEMISTRY, 1985, 24 (07) :1561-1565

[10]

Protective effects of steroid saponins from Paris polyphylla var. yunnanensis on ethanol- or indomethacin-induced gastric mucosal lesions in rats:: Structural requirement for activity and mode of action [J].

Matsuda, H ;

Pongpiriyadacha, Y ;

Morikawa, T ;

Kishi, A ;

Kataoka, S ;

Yoshikawa, M .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (06) :1101-1106

← 1 2 3 →