Lipase-mediated resolution of cis-1-amino-2-indanol, the key component of the HIV protease inhibitor indinavir

被引：13

作者：

Anilkumar, AT ^{[1
]}

Goto, K ^{[1
]}

Takahashi, T ^{[1
]}

Ishizaki, K ^{[1
]}

Kaga, H ^{[1
]}

机构：

[1] Hokkaido Natl Ind Res Inst, Sapporo, Hokkaido 0628517, Japan

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 13期

关键词：

D O I：

10.1016/S0957-4166(99)00260-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The efficient and direct resolution of cis-1-amino-2-indanol using Candida antarctica lipase B catalyzing the alcoholysis of its N,O-diacetyl derivative is reported. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2501 / 2503

页数：3

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