Effect of Far Infrared Drying on Antioxidant Property, Anti-inflammatory Activity, and Inhibitory Activity in A549 Cells of Gamguk (Chrysanthemum indicum L.) Flower

被引：18

作者：

Kim, Won-Woo ^{[1
]}

Ghimeray, Amal Kumar ^{[1
]}

Wu, Jin Cheng ^{[1
]}

Eom, Seok Hyun ^{[2
]}

Lee, Beom-Goo ^{[3
]}

Kang, Wie-Soo ^{[1
]}

Cho, Dong-Ha ^{[1
]}

机构：

[1] Kangwon Natl Univ, Coll Biomed Sci, Chunchon 200701, Gangwon, South Korea

[2] Kyung Hee Univ, Yongin 446701, Gyeonggi, South Korea

[3] Korea Energy Technol, Seoul 153772, South Korea

来源：

FOOD SCIENCE AND BIOTECHNOLOGY | 2012年 / 21卷 / 01期

关键词：

gamguk (Chrysanthemum indicum L.); far infrared ray; polyphenol; anti-inflammatory; A549; RADIATION; PRODUCTS;

D O I：

10.1007/s10068-012-0034-0

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-alpha, cyclooxygenase (COX)-2 expression, and prostaglandis E-2 (PGE(2)) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0.05) higher in dose and time dependent manner.

引用

页码：261 / 265

页数：5

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