Severe axonal polyneuropathy after a FK506 overdosage in a lung transplant recipient

被引:9
作者
Boukriche, Y
Brugière, O
Castier, Y
Stocco, J
Mal, H
Fournier, M
机构
[1] Hop Beaujon, Dept Neurol, F-92110 Clichy, France
[2] Hop Beaujon, Dept Pneumol, F-92110 Clichy, France
[3] Hop Beaujon, Dept Thorac Surg, F-92110 Clichy, France
[4] Hop Beaujon, Dept Pharmaceut, F-92110 Clichy, France
关键词
D O I
10.1097/00007890-200112150-00026
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
FK506-induced polyneuropathies are rarely encountered. We report a case of axonal sensorimotor polyneuropathy in a lung transplant recipient that occurred during a FK506 overdosage. Onset was acute in the form of severe areflexic tetraparesis and resolution was observed after reduction of dosage. Because of increasing use of FK506 in solid organ transplantation, caution should be paid with FK506 dosage monitoring in cases of peripheral nervous system symptoms.
引用
收藏
页码:1849 / 1850
页数:2
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