Cytokines and Cancer Anorexia Cachexia Syndrome

被引:44
作者
Bennani-Baiti, Nabila [1 ]
Davis, Mellar P. [1 ]
机构
[1] Cleveland Clin, Harry R Horvitz Ctr Palliat Med, Taussig Canc Ctr, Cleveland, OH 44195 USA
关键词
cancer; cytokines; cancer-related cachexia; anorexia; tissue wasting;
D O I
10.1177/1049909108315518
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Cancer anorexia cachexia syndrome is frequent yet still a not well understood cancer-related problem. The pathophysiology of cancer cachexia is multifactorial. It is suggested to be the result of tumor-host interactions and studies of the disturbances seen during cancer anorexia cachexia syndrome, such as anorexia, hypermetabolism, tissue wasting, metabolic abnormalities, and hormonal changes, all point to the involvement in one way or another of one key factor: cytokines. The purpose of this review is to summarize the latest developments in the field of cytokines and their role in cancer anorexia cachexia syndrome. The emphasis is on the role of cytokines in anorexia and tissue wasting.
引用
收藏
页码:407 / 411
页数:5
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