Nonlinear side effects of fs pulses inside corneal tissue during photodisruption

被引:65
作者
Heisterkamp, A
Ripken, T
Mamom, T
Drommer, W
Welling, H
Ertmer, W
Lubatschowski, H
机构
[1] Laser Zentrum Hannover EV, D-30419 Hannover, Germany
[2] Tierarztlichen Hsch Hannover, Inst Pathol, D-30559 Hannover, Germany
[3] Univ Hannover, Inst Quantenopt, D-30167 Hannover, Germany
来源
APPLIED PHYSICS B-LASERS AND OPTICS | 2002年 / 74卷 / 4-5期
关键词
D O I
10.1007/s003400200825
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In order to evaluate the potential for refractive surgery, fs laser pulses of 150-fs pulse duration were used to process corneal tissue of dead and living animal eyes. By focusing the laser radiation down to spot sizes of several microns, very precise cuts could be achieved inside the treated cornea, accompanied with minimum collateral damage to the tissue by thermal or mechanical effects. During histo-pathological analysis by light and transmission electron microscopy considerable side effects of fs photodisruption were found. Due to the high intensities at the focal region several nonlinear effects occurred. Self-focusing, photodissociation, UV-light production were observed, leading to streak formation inside the cornea.
引用
收藏
页码:419 / 425
页数:7
相关论文
共 18 条
[1]  
Boyd R. W., 2003, NONLINEAR OPTICS
[2]   Theory and simulation on the threshold of water breakdown induced by focused ultrashort laser pulses [J].
Feng, Q ;
Moloney, JV ;
Newell, AC ;
Wright, EM ;
Cook, K ;
Kennedy, PK ;
Hammer, DX ;
Rockwell, BA ;
Thompson, CR .
IEEE JOURNAL OF QUANTUM ELECTRONICS, 1997, 33 (02) :127-137
[3]   Intrastromal cutting effects in rabbit cornea using femtosecond laser pulses [J].
Heisterkamp, A ;
Ripken, T ;
Lubatschowski, H ;
Welling, H ;
Lütkefels, E ;
Drommer, W ;
Ertmer, W .
OPTICAL BIOPSY AND TISSUE OPTICS, 2000, 4161 :52-60
[4]   Corneal refractive surgery with femtosecond lasers [J].
Juhasz, T ;
Frieder, H ;
Kurtz, RM ;
Horvath, C ;
Bille, JF ;
Mourou, G .
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) :902-910
[5]   FEMTOSECOND-PULSE LASER-ABLATION OF HUMAN CORNEAS [J].
KAUTEK, W ;
MITTERER, S ;
KRUGER, J ;
HUSINSKY, W ;
GRABNER, G .
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 1994, 58 (05) :513-518
[6]   Nanodissection of human chromosomes with near-infrared femtosecond laser pulses [J].
König, K ;
Riemann, I ;
Fritzsche, W .
OPTICS LETTERS, 2001, 26 (11) :819-821
[7]  
LIU X, 1997, OSA TECHNICAL DIGEST, V11, P169
[8]   Non-thermal ablation of neural tissue with femtosecond laser pulses [J].
Loesel, FH ;
Fischer, JP ;
Gotz, MH ;
Horvath, C ;
Juhasz, T ;
Noack, F ;
Suhm, N ;
Bille, JF .
APPLIED PHYSICS B-LASERS AND OPTICS, 1998, 66 (01) :121-128
[9]   Application of ultrashort laser pulses for intrastromal refractive surgery [J].
Lubatschowski, H ;
Maatz, G ;
Heisterkamp, A ;
Hetzel, U ;
Drommer, W ;
Welling, H ;
Ertmer, W .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2000, 238 (01) :33-39
[10]   Chemical and physical side effects at application of ultrashort laser pulses for intrastromal refractive surgery [J].
Maatz, G ;
Heisterkamp, A ;
Lubatschowski, H ;
Barcikowski, S ;
Fallnich, C ;
Welling, H ;
Ertmer, W .
JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS, 2000, 2 (01) :59-64