Primary Prevention of Atherosclerosis A Clinical Challenge for the Reversal of Epigenetic Mechanisms?

被引:108
作者
Napoli, Claudio [1 ,2 ]
Crudele, Valeria [1 ]
Soricelli, Andrea [2 ,3 ]
Al-Omran, Mohammed [4 ]
Vitale, Nicoletta [5 ]
Infante, Teresa [2 ]
Mancini, Francesco P. [5 ]
机构
[1] Univ Naples 2, Sch Med 1,Azienda Univ Policlin, Excellence Res Ctr Cardiovasc Dis,Reg Reference L, Dept Gen Pathol,UOC Immunohematol Transfus Med &, I-80138 Naples, Italy
[2] Fdn SDN, Ist Ricovero & Cura Carattere Sci, Naples, Italy
[3] Parthenope Univ, Naples, Italy
[4] King Saud Univ, Coll Med, Peripheral Vasc Dis Res Chair, Riyadh 11461, Saudi Arabia
[5] Univ Sannio, Dept Sci Biol Geol & Environm, Benevento, Italy
关键词
primary prevention; epigenetics; statins; CARDIOVASCULAR RISK-FACTORS; RANDOMIZED CONTROLLED-TRIAL; ABDOMINAL AORTIC-ANEURYSM; RENIN-ANGIOTENSIN SYSTEM; GENOME-WIDE ASSOCIATION; FATTY STREAK FORMATION; SMOOTH-MUSCLE-CELLS; C-REACTIVE PROTEIN; MATERNAL-HYPERCHOLESTEROLEMIA; DNA METHYLATION;
D O I
10.1161/CIRCULATIONAHA.111.085787
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2363 / 2373
页数:11
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