TIM-1 and TIM-3 proteins in immune regulation

被引：134

作者：

Su, Ee Wern ^{[1
]}

Lin, Jean Y. ^{[1
]}

Kane, Lawrence P. ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Immunol, Pittsburgh, PA 15261 USA

来源：

CYTOKINE | 2008年 / 44卷 / 01期

关键词：

T cells; Macrophages; Apoptosis; Activation; Tolerance;

D O I：

10.1016/j.cyto.2008.06.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Over the last several years, there has been increasing interest in the role of proteins of the TIM (T cell immunoglobulin and mucin domain) family in regulating immune responses. Despite what the name suggests, proteins of this family function in a Much more widespread manner than just on T cells, as we will discuss in this review. We therefore propose that the definition of TIM be adjusted to "transmembrane immunoglobulin and mucin". (C) 2008 Elsevier Ltd. All rights reserved.

引用

收藏

页码：9 / 13

页数：5

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