Non-aqueous reduction of aromatic sulfonyl chlorides to thiols using a dichlorodimethylsilane-zinc-dimethylacetamide system

被引：31

作者：

Uchiro, H ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Sci Univ Tokyo, Fac Pharmaceut Sci, Shinjuku Ku, Tokyo 1620862, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(99)00408-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and efficient method for the non-aqueous reduction of sulfonyl chlorides to affored the corresponding thiols by use of a dichlorodimethylsilane-zinc-dimethylacetamide system was successfully developed. Various aromatic thiols were prepared in high yield by easy operation. Continuous reactions with the above reduction using the prepared thiol were also demonstrated. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3179 / 3182

页数：4

共 16 条

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