Laryngeal long latency response conditioning in abductor spasmodic dysphonia

被引：19

作者：

Deleyiannis, FWB ^{[1
]}

Gillespie, M ^{[1
]}

Bielamowicz, S ^{[1
]}

Yamashita, T ^{[1
]}

Ludlow, CL ^{[1
]}

机构：

[1] Natl Inst Deafness & Other Commun Disorders, Voice & Speech Sect, Div Intramural Res, Bethesda, MD 20892 USA

来源：

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | 1999年 / 108卷 / 06期

关键词：

abductor spasmodic dysphonia; electromyography; laryngeal long latency response;

D O I：

10.1177/000348949910800615

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

previously we demonstrated that patients with adductor spasmodic dysphonia (ADSD) have a disinhibition of laryngeal responses to sensory input. In this study, sensorimotor responses to stimulation of the superior laryngeal nerve were compared between 10 subjects with abductor spasmodic dysphonia (ABSD) and 15 normal volunteers. The groups had similar latency and frequency characteristics of their unconditioned adductor responses (p >.05). The conditioned R1 (early) responses of the subjects with ABSD were greater and more variable in amplitude than those of the normal volunteers (p less than or equal to.008). Similar R2 (late) conditioning effects were found in both groups, with a nonsignificant trend toward reduced inhibition of contralateral R2 responses at lower interstimulus intervals (p =.01) in the patient group. Thus, inhibitory mechanisms that modulate the R1 laryngeal sensorimotor pathway in the brain stem may be abnormal in subjects with ABSD. Abnormal modulation of laryngeal sensorimotor responses seems present in both types of spasmodic dysphonia.

引用

页码：612 / 619

页数：8

共 30 条

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