Wound dressing based on nonwoven viscose fabrics

被引：51

作者：

Abou-Okeil, A. ^{[1
]}

Sheta, A. M. ^{[2
]}

Amr, A. ^{[1
]}

Ali, Marwa A. ^{[1
]}

机构：

[1] Natl Res Ctr, Text Res Div, Cairo, Egypt

[2] Cairo Univ, Fac Vet, Cairo, Egypt

来源：

CARBOHYDRATE POLYMERS | 2012年 / 90卷 / 01期

关键词：

Wound dressing; Chitosan; PVA; Ag nanoparticles; Nonwoven viscose fabric; Wound healing; POLY(VINYL ALCOHOL); ANTIBACTERIAL PROPERTIES; SILVER NANOPARTICLES; BLOOD COMPATIBILITY; CHITOSAN MEMBRANES; IN-VITRO; SKIN; PERMEABILITY; DELIVERY; RELEASE;

D O I：

10.1016/j.carbpol.2012.05.093

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Nonwoven viscose fabric was treated with chitosan/polyvinyl alcohol (PVA) using pad-dry method, using different concentrations of chitosan and PVA. Increasing the amount of PVA leads to increasing of air permeability. Water permeability increased by increasing the amount of PVA to 2 ml (10% solution) then decreased by any increase of the quantity of PVA solution. Roughness increased with increasing the amount of 10% PVA solution. It is shown that roughness, water and air permeability increased with increasing the chitosan concentration. Antibacterial properties was increased with increasing PVA/or chitosan concentration. The chitosan/PVA treated nonwoven viscose fabric was immersed in a solution of Ag nanoparticles. The chitosan/PVA/Ag nanoparticles treated nonwoven fabrics were used as wound dressings on French white Bouscat rabbits, with age ranged from 1 to 2 years. A complete healing was achieved using wound dressing consists of nonwoven viscose fabric treated with chitosan/PVA/Ag nanoparticles after 21 days. The histopathological examination confirmed the complete re-epithelialization and averagely thick epidermis formation. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：658 / 666

页数：9

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