Cytogenetics and molecular genetics in multiple myeloma

被引：59

作者：

Feinman, R ^{[1
]}

Sawyer, J ^{[1
]}

Hardin, J ^{[1
]}

Tricot, G ^{[1
]}

机构：

[1] UNIV ARKANSAS MED SCI HOSP,DIV HEMATOL ONCOL,LITTLE ROCK,AR 72205

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1997年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0889-8588(05)70412-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Specific cytogenetic abnormalities have been identified in multiple myeloma that confer a poor prognosis, even with intensive chemotherapy and autotransplants. The identification and characterization of potential genes involved in these different chromosomal changes and their interplay with oncogenes and tumor suppressor genes controlling cellular growth and apoptosis is the major focus of this review.

引用

页码：1 / &

页数：26

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