Qualitative and quantitative micellar electrokinetic chromatography of kavalactones from dry extracts of Piper methysticum Forst. and commercial drugs

被引：15

作者：

Lechtenberg, M

Quandt, B

Kohlenberg, FJ

Nahrstedt, A

机构：

[1] Inst Pharmazeut Biol & Phytochem, D-48149 Munster, Germany

[2] Inst Pharmakol & Toxikol, D-48149 Munster, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 848卷 / 1-2期

关键词：

Piper methysticum; pharmaceutical analysis; plant materials; kavalactones; styrylpyrones;

D O I：

10.1016/S0021-9673(99)00425-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

A rapid micellar electrokinetic chromatography method with diode-array detection has been developed for the identification and quantitative determination of the therapeutically important styrylpyrones from Piper methysticum extracts and commercial drugs. Using fused-silica capillaries with a berate buffer containing sodium-taurodeoxycholic acid and beta-cyclodextrin kavain, dihydrokavain, methysticin, dihydromethysticin, yangonin and demethoxyyangonin were fully separated and quantified within 15 min with 4-hydroxybenzoic acid methyl ester as I.S. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：457 / 464

页数：8

共 20 条

[1]

Contribution to the quantitative and enantioselective determination of kavapyrones by high-performance liquid chromatography on ChiraSpher NT material [J].