共 19 条
Electrogram-guided substrate ablation with or without pulmonary vein isolation in patients with persistent atrial fibrillation
被引:57
作者:

Estner, Heidi Luise
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机构:
Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Hessling, Gabriele
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h-index: 0
机构:
Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Ndrepepa, Gjin
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h-index: 0
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Wu, JinJin
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h-index: 0
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Reents, Tilko
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Fichtner, Stefanie
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h-index: 0
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Schmitt, Claus
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h-index: 0
机构:
Stadt Klinikum Karlsruhe, Karlsruhe, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Bary, Christian V.
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Kolb, Christof
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h-index: 0
机构:
Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Karch, Martin
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h-index: 0
机构:
Stadt Klinikum Karlsruhe, Karlsruhe, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Zrenner, Bernhard
论文数: 0 引用数: 0
h-index: 0
机构:
Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany

Deisenhofer, Isabel
论文数: 0 引用数: 0
h-index: 0
机构:
Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
机构:
[1] Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-80636 Munich, Germany
[2] Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-80636 Munich, Germany
[3] Stadt Klinikum Karlsruhe, Karlsruhe, Germany
来源:
EUROPACE
|
2008年
/
10卷
/
11期
关键词:
Persistent atrial fibrillation;
Ablation;
Pulmonary vein isolation;
Complex fractionated atrial electrograms;
D O I:
10.1093/europace/eun244
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Aims Ablation of complex fractionated atrial electrograms (CFAEs) is a new approach for the treatment of atrial fibrillation (AF). The purpose of the study was to assess the efficacy of CFAE ablation as a stand-alone strategy in patients with persistent AF and to compare it with a combined approach of CFAE ablation and pulmonary vein isolation (PVI). Methods and results The study included 77 consecutive patients with persistent AF who underwent radiofrequency (RF) ablation of CFAE as a sole ablation procedure (CFAE group, n = 23 patients) or a combined approach of CFAE ablation and PVI (CFAE plus PVI group, n = 54 patients). Procedures were guided by three-dimensional mapping systems. After the procedure, AF recurrences were evaluated with 7-day Holter recordings at 1, 3, and 6 months and every 6 months thereafter. Treatment failure was defined as >= 1 AF episode lasting > 30 s on Holter recordings during follow-up. After a mean follow-up time of 13 +/- 10 months, 2 of 23 patients (9%) with CFAE ablation and 22 of 54 patients (41%) with CFAE plus PVI were in sinus rhythm after a single ablation procedure without anti-arrhythmic medication (P = 0.008). Conclusion Ablation of CFAE as a stand-alone ablation strategy seems insufficient for the treatment of patients with persistent AF. Pulmonary vein isolation plus CFAE ablation significantly increases the mid-term success rate.
引用
收藏
页码:1281 / 1287
页数:7
相关论文
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Hessling, Gabriele
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Ndrepepa, Gjin
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Luik, Armin
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

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Stadt Klinikum Karlsruhe, Karlsruhe, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Konietzko, Agathe
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Ekrem, Uecer
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

Wu, JinJin
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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

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Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany

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Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 1, D-8000 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Deutsch Herzzentrum Munchen, D-8000 Munich, Germany
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机构: UNIV WESTERN ONTARIO, DEPT MED, LONDON, ON, CANADA

JONES, DL
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机构: UNIV WESTERN ONTARIO, DEPT MED, LONDON, ON, CANADA

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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

McKenzie, J
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

Kosar, E
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

Schwab, M
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

Sunsaneewitayakul, B
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

Vasavakul, T
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

Khunnawat, C
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机构: Pacific Rim Electrophysiol Res Inst, Inglewood, CA 90301 USA

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Scharf, C
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Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Chugh, A
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h-index: 0
机构:
Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Hall, B
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Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Cheung, P
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h-index: 0
机构:
Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Good, E
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机构:
Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Veerareddy, S
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Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Pelosi, F
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机构:
Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Div Cardiol, Ann Arbor, MI 48109 USA

Morady, F
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Knight, BP
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Tada, H
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Özaydin, M
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Chugh, A
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Hassan, S
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Scharf, C
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Lai, SWK
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Greenstein, R
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Pelosi, F
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h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Strickberger, SA
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA

Morady, F
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA