Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

被引：38

作者：

Fukudo, S ^{[1
]}

Abe, K ^{[1
]}

Hongo, M ^{[1
]}

Utsumi, A ^{[1
]}

Itoyama, Y ^{[1
]}

机构：

[1] TOHOKU UNIV,SCH MED,DEPT NEUROL,AOBA KU,SENDAI,MIYAGI 98077,JAPAN

来源：

BRAIN RESEARCH | 1997年 / 757卷 / 01期

关键词：

heat shock protein (HSP)70; restraint water-immersion stress; cerebral-cortex; stomach; rat; messenger RNA; Northern blotting;

D O I：

10.1016/S0006-8993(97)00179-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated bg Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.

引用

页码：146 / 148

页数：3

共 12 条

[1] DISSOCIATION OF HSP70 AND HSC70 HEAT-SHOCK MESSENGER-RNA INDUCTIONS AS AN EARLY BIOCHEMICAL MARKER OF ISCHEMIC NEURONAL DEATH
ABE, K
KAWAGOE, J
AOKI, M
KOGURE, K
[J]. NEUROSCIENCE LETTERS, 1993, 149 (02) : 165 - 168
[2] IMMUNOHISTOCHEMICAL STUDIES OF NORADRENERGIC-INDUCED EXPRESSION OF C-FOS IN THE RAT CNS
BING, GY
STONE, EA
ZHANG, Y
FILER, D
[J]. BRAIN RESEARCH, 1992, 592 (1-2) : 57 - 62
[3] RAPID CHANGES IN EXTRACELLULAR GLUCOSE-LEVELS AND BLOOD-FLOW IN THE STRIATUM OF THE FREELY MOVING RAT
FELLOWS, LK
BOUTELLE, MG
[J]. BRAIN RESEARCH, 1993, 604 (1-2) : 225 - 231
[4] FUKUDO FS, 1993, PSYCHOM MED, V55, P113
[5] PSYCHOPHYSIOLOGICAL STRESS INDUCES HEAT-SHOCK COGNATE PROTEIN (HSC)70 MESSENGER-RNA IN THE CEREBRAL-CORTEX AND STOMACH OF RATS
FUKUDO, S
ABE, K
HONGO, M
UTSUMI, A
ITOYAMA, Y
[J]. BRAIN RESEARCH, 1995, 675 (1-2) : 98 - 102
[6] REGULATION OF HEAT-SHOCK PROTEIN-70 GENE-EXPRESSION BY C-MYC
KINGSTON, RE
BALDWIN, AS
SHARP, PA
[J]. NATURE, 1984, 312 (5991) : 280 - 282
[7] OXIDANT STRESS INCREASES HEAT-SHOCK PROTEIN-70 MESSENGER-RNA IN ISOLATED-PERFUSED RAT-HEART
KUKREJA, RC
KONTOS, MC
LOESSER, KE
BATRA, SK
QIAN, YZ
GBUR, CJ
NASEEM, SA
JESSE, RL
HESS, ML
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1994, 267 (06): : H2213 - H2219
[8] STRESS INDUCES NEURONAL DEATH IN THE HIPPOCAMPUS OF CASTRATED RATS
MIZOGUCHI, K
KUNISHITA, T
CHUI, DH
TABIRA, T
[J]. NEUROSCIENCE LETTERS, 1992, 138 (01) : 157 - 160
[9] CELLS IN STRESS - TRANSCRIPTIONAL ACTIVATION OF HEAT-SHOCK GENES
MORIMOTO, RI
[J]. SCIENCE, 1993, 259 (5100) : 1409 - 1410
[10] SYNTHESIS OF HEAT-SHOCK STRESS PROTEINS DURING CELLULAR INJURY
NOWAK, TS
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1993, 679 : 142 - 156

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