Possible Role for Tocilizumab, an Anti-Interleukin-6 Receptor Antibody, in Treating Cancer Cachexia

被引：101

作者：

Ando, Katsutoshi ^{[1
,2
]}

Takahashi, Fumiyuki ^{[1
]}

Motojima, Shinji ^{[2
]}

Nakashima, Kei ^{[2
]}

Kaneko, Norihiro ^{[2
]}

Hoshi, Kazuei ^{[2
]}

Takahashi, Kazuhisa ^{[1
]}

机构：

[1] Juntendo Univ, Grad Sch Med, Tokyo, Japan

[2] Kameda Med Ctr, Chiba, Japan

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2013年 / 31卷 / 06期

基金：

日本学术振兴会;

关键词：

DOUBLE-BLIND; RHEUMATOID-ARTHRITIS; EICOSAPENTAENOIC ACID; CASTLEMAN-DISEASE; INTERLEUKIN-6; ANOREXIA/CACHEXIA; APPETITE;

D O I：

10.1200/JCO.2012.44.2020

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：E69 / E72

页数：4

共 14 条

[1] Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: A double-blind, placebo-controlled study [J].

Bruera, E ;

Strasser, F ;

Palmer, JL ;

Willey, J ;

Calder, K ;

Amyotte, G ;

Baracos, V .

JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (01) :129-134

[2]

BRUERA E, 1985, CANCER TREAT REP, V69, P751

[3] Appetite and cancer-associated anorexia: A review [J].

Davis, MP ;

Dreicer, R ;

Walsh, D ;

Lagman, R ;

LeGrand, SB .

JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (08) :1510-1517

[4] Double-blind, placebo-controlled, randomized study of eicosapentaenoic acid diester in patients with cancer cachexia [J].

Fearon, Kenneth C. H. ;

Barber, Matthew D. ;

Moses, Alastair G. ;

Ahmedzai, Sam H. ;

Taylor, Gillian S. ;

Tisdale, Michael J. ;

Murray, Gordon D. .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (21) :3401-3407

[5] EXCESSIVE PRODUCTION OF INTERLEUKIN-6/B CELL STIMULATORY FACTOR-II IN RHEUMATOID-ARTHRITIS [J].

HIRANO, T ;

MATSUDA, T ;

TURNER, M ;

MIYASAKA, N ;

BUCHAN, G ;

TANG, B ;

SATO, K ;

SHIMIZU, M ;

MAINI, R ;

FELDMAN, M ;

KISHIMOTO, T .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1988, 18 (11) :1797-1801

[6] Interleukin-6: From basic science to medicine - 40 years in immunology [J].

Kishimoto, T .

ANNUAL REVIEW OF IMMUNOLOGY, 2005, 23 :1-21

[7] Interleukin 6 is associated with cachexia in patients with prostate cancer [J].

Kuroda, Kenji ;

Nakashima, Jun ;

Kanao, Kent ;

Kikuchi, Eiji ;

Miyajima, Akira ;

Horiguchi, Yutaka ;

Nakagawa, Ken ;

Oya, Mototsugu ;

Ohigashi, Takashi ;

Murai, Masaru .

UROLOGY, 2007, 69 (01) :113-117

[8] Randomized comparison of megestrol acetate versus dexamethasone versus fluoxymesterone for the treatment of cancer anorexia/cachexia [J].

Loprinzi, CL ;

Kugler, JW ;

Sloan, JA ;

Mailliard, JA ;

Krook, JE ;

Wilwerding, MB ;

Rowland, KM ;

Camoriano, JK ;

Novotny, PJ ;

Christensen, BJ .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (10) :3299-3306

[9] Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody - A multicenter, double-blind, placebo-controlled trial [J].

Nishimoto, N ;

Yoshizaki, K ;

Miyasaka, N ;

Yamamoto, K ;

Kawai, S ;

Takeuchi, T ;

Hashimoto, J ;

Azuma, J ;

Kishimoto, T .

ARTHRITIS AND RHEUMATISM, 2004, 50 (06) :1761-1769

[10] Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease [J].

Nishimoto, N ;

Kanakura, Y ;

Aozasa, K ;

Johkoh, T ;

Nakamura, M ;

Nakano, S ;

Nakano, N ;

Ikeda, Y ;

Sasaki, T ;

Nishioka, K ;

Hara, M ;

Taguchi, H ;

Kimura, Y ;

Kato, Y ;

Asaoku, H ;

Kumagai, S ;

Kodama, F ;

Nakahara, H ;

Hagihara, K ;

Yoshizaki, K ;

Kishimoto, T .

BLOOD, 2005, 106 (08) :2627-2632

← 1 2 →