Ropinirole for restless legs syndrome - A placebo-controlled crossover trial

被引：64

作者：

Adler, CH

Hauser, RA

Sethi, K

Caviness, JN

Marlor, L

Anderson, WM

Hentz, JG

机构：

[1] Mayo Clin Scottsdale, Dept Neurol, Parkinsons Dis & Movement Disorders Ctr, Scottsdale, AZ 85259 USA

[2] Mayo Clin Scottsdale, Dept Biostat, Scottsdale, AZ 85259 USA

[3] Univ S Florida, Dept Neurol, Tampa, FL 33620 USA

[4] Univ S Florida, Dept Pharmacol, Tampa, FL 33620 USA

[5] Univ S Florida, Dept Expt Therapeut, Tampa, FL 33620 USA

[6] Univ S Florida, Dept Internal Med, Tampa, FL 33620 USA

[7] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA

来源：

NEUROLOGY | 2004年 / 62卷 / 08期

关键词：

D O I：

10.1212/01.WNL.0000120672.94060.F1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors performed a double-blind, placebo-controlled, crossover study of ropinirole (0.5 to 6.0 mg/day) for restless legs syndrome (RLS). The RLS Rating Scale score improved (p < 0.001) from a mean (SD) of 25 (7) during placebo treatment to 13 (12) during ropinirole treatment. Eight of the 22 patients had complete resolution of symptoms on ropinirole. Adverse events included nausea and dizziness. Ropinirole was effective and well tolerated for treating the symptoms of RLS.

引用

页码：1405 / 1407

页数：3

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