Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state

被引：100

作者：

Hayashi, Yujiro ^{[1
]}

Matsuzawa, Masayoshi

Yamaguchi, Junichiro

Yonehara, Sayaka

Matsumoto, Yasunobu

Shoji, Mitsuru

Hashizume, Daisuke

Koshino, Hiroyuki

机构：

[1] Tokyo Univ Sci, Fac Engn, Dept Ind Chem, Shinjuku Ku, Tokyo 1628601, Japan

[2] RIKEN, Wako, Saitama 3510198, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 28期

关键词：

amino acids; asymmetric catalysis; carbohydrates; chirality; proline;

D O I：

10.1002/anie.200601506

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A clue to the origin of chirality? A solution of proline with high enantiomeric excess (85-99% ee) was obtained from solid proline of only 10% ee through novel dissolution and crystallization processes (see scheme). This observation may be an explanation for the origin of chirality on Earth. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4593 / 4597

页数：5

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