Antimicrobial susceptibility of 1,422 Haemophilus influenzae isolates from respiratory tract infections in Spain.: Results of a 1-year (1996-97) multicenter surveillance study

被引：21

作者：

García-Rodríguez, JA

Baquero, F

de Lomas, JG

Aguilar, L

机构：

[1] SmithKline Beecham Pharmaceut, Dept Med, E-28034 Madrid, Spain

[2] Univ Hosp Salamanca, E-37007 Salamanca, Spain

[3] Hosp Ramon & Cajal, E-28034 Madrid, Spain

[4] Inst Valenciano Microbiol, E-46117 Valencia, Spain

[5] Hosp La Paz, Madrid, Spain

[6] Hosp Gen Gregorio Maranon, Madrid, Spain

[7] Xeral Galicia Hosp, Santiago De Compostela, Spain

[8] Virgen Macarena Hosp, Seville, Spain

[9] Clin Univ Hosp, Barcelona, Spain

[10] Univ Hosp Zaragoza, Zaragoza, Spain

[11] Virgen Nieves Hosp, Granada, Spain

[12] Reina Sofia Hosp, Cordoba, Spain

[13] Basurto Hosp, Bilbao, Spain

[14] Univ Hosp Salamanca, Salamanca, Spain

[15] Santa Creu & San Pau Hosp, Barcelona, Spain

[16] Hosp Insular, Las Palmas Gran Canaria, Spain

[17] Infanta Cristina Hosp, Badajoz, Spain

[18] Inst Valenciano Microbiol, Valencia, Spain

[19] SmithKline Beecham Pharmaceut, Madrid, Spain

来源：

INFECTION | 1999年 / 27卷 / 4-5期

关键词：

Penicillin; Production Rate; Respiratory Tract; Respiratory Tract Infection; Amoxicillin;

D O I：

10.1007/s150100050026

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A Haemophilus influenzae multicenter antimicrobial susceptibility surveillance was carried out. An overall beta-lactamase production rate of 25.7% was found, with significant differences between hospitals ranging between 7.9 and 47.9%. Presumable intrinsic resistance was found in 4.6% of strains. No differences in susceptibility were observed between beta-lactamase positive and beta-lactamase negative strains for all antibiotics, except for penicillin, amoxicillin and cefaclor, A higher prevalence of resistance was found for clarithromycin vs azithromycin (22.6 vs 0.7%). Differences in all these factors make surveillance essential as a guideline for empiric treatment in community-acquired respiratory tract infections.

引用

页码：265 / 267

页数：3

共 7 条

[1] Susceptibility surveillance of US respiratory pathogen isolates to newer macrolide and azalide antibiotics [J].