Spectrum of clinical presentation, treatment and prognosis in a series of eight patients with leukaemia cutis

被引:68
作者
Watson, KMT
Mufti, G
Salisbury, JR
Vivier, AWP
Creamer, D
机构
[1] Kings Coll London, Dept Dermatol, London SE5 9RS, England
[2] Kings Coll London, Dept Haematol, London, England
[3] Kings Coll London, Dept Histopathol, London, England
关键词
D O I
10.1111/j.1365-2230.2005.02022.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
All types of leukaemia can disseminate to the skin, producing cutaneous deposits known as leukaemia cutis (LC). We undertook a retrospective study to review the clinical presentations, treatment and outcome of eight patients with LC managed in our department over a period of 12 years. The clinical phenotype varied, with erythematous papules and nodules occurring with greatest frequency. Infiltrated haemorrhagic plaques and perifollicular acneiform papules were also seen. Although patients were treated aggressively for their underlying leukaemia, and received therapy directed towards LC, they tended to be refractory to treatment and the diagnosis was generally associated with a poor prognosis. The exception was a patient with chronic lymphocytic leukaemia, who survived 3 years after developing LC.
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收藏
页码:218 / 221
页数:4
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