Asymmetric deprotonation of N,N-dihexyl-1-naphthamides to provide atropisomers of N,N-dihexyl-2-alkyl-1-naphthamides

被引：73

作者：

Thayumanavan, S

Beak, P

Curran, DP

机构：

[1] UNIV ILLINOIS, DEPT CHEM, URBANA, IL 61801 USA

[2] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 17期

关键词：

D O I：

10.1016/0040-4039(96)00439-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric deprotonation of N,N-dihexyl-1-naphthamide using sec-butyllithium / (-)-sparteine followed by reactions with methyl or ethyl alkylation reagents give the atropisomers of N,N-dihexyl-2-alkyl-1-naphthamide with 50% and 55% ee, respectively. (C) 1996 Elsevier Science Ltd

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页码：2899 / 2902

页数：4

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