Neoadjuvant procarbazine, CCNU, and vincristine for anaplastic and aggressive oligodendroglioma

被引：54

作者：

Paleologos, NA

Macdonald, DR

Vick, NA

Cairncross, JG

机构：

[1] Northwestern Univ, Evanston Hosp, Div Neurol, Evanston, IL 60201 USA

[2] London Reg Canc Ctr, London, ON N6A 4L6, Canada

来源：

NEUROLOGY | 1999年 / 53卷 / 05期

关键词：

oligodendroglioma; chemotherapy; neoadjuvant;

D O I：

10.1212/WNL.53.5.1141

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors reviewed the results of neoadjuvant (preradiation) procarbazine, CCNU, and vincristine chemotherapy for anaplastic oligodendrogliomas because, increasingly, chemotherapy is prescribed before radiation for oligodendroglial neoplasms. The data indicate that 70% of patients respond to neoadjuvant chemotherapy, whereas 30% require early radiation because they either have chemoresistant tumors or experience unacceptable chemotoxicity.

引用

收藏

页码：1141 / 1143

页数：3

相关论文

共 8 条

[1] CHEMOTHERAPY FOR ANAPLASTIC OLIGODENDROGLIOMA [J].

CAIRNCROSS, G ;

MACDONALD, D ;

LUDWIN, S ;

LEE, D ;

CASCINO, T ;

BUCKNER, J ;

FULTON, D ;

DROPCHO, E ;

STEWART, D ;

SCHOLD, C ;

WAINMAN, N ;

EISENHAUER, E .

JOURNAL OF CLINICAL ONCOLOGY, 1994, 12 (10) :2013-2021

[2]

CAIRNCROSS G, 1997, AM SOC CLIN ONCOL, V16, pA388

[3] CHEMOTHERAPY FOR OLIGODENDROGLIOMA - PROGRESS REPORT [J].

CAIRNCROSS, JG ;

MACDONALD, DR .

ARCHIVES OF NEUROLOGY, 1991, 48 (02) :225-227

[4] Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas [J].

Cairncross, JG ;

Ueki, K ;

Zlatescu, MC ;

Lisle, DK ;

Finkelstein, DM ;

Hammond, RR ;

Silver, JS ;

Stark, PC ;

Macdonald, DR ;

Ino, Y ;

Ramsay, DA ;

Louis, DN .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (19) :1473-1479

[5] Oligodendrogliomas .1. Patterns of growth, histological diagnosis, clinical and imaging correlations: A study of 153 cases [J].

DaumasDuport, C ;

Varlet, P ;

Tucker, ML ;

Beuvon, F ;

Cervera, P ;

Chodkiewicz, JP .

JOURNAL OF NEURO-ONCOLOGY, 1997, 34 (01) :37-59

[6] THE TREATMENT OF OLIGODENDROGLIOMAS AND MIXED OLIGODENDROGLIOMA-ASTROCYTOMAS WITH PCV CHEMOTHERAPY [J].

GLASS, J ;

HOCHBERG, FH ;

GRUBER, ML ;

LOUIS, DN ;

SMITH, D ;

RATTNER, B .

JOURNAL OF NEUROSURGERY, 1992, 76 (05) :741-745

[7] SUCCESSFUL CHEMOTHERAPY FOR NEWLY DIAGNOSED AGGRESSIVE OLIGODENDROGLIOMA [J].

MACDONALD, DR ;

GASPAR, LE ;

CAIRNCROSS, JG .

ANNALS OF NEUROLOGY, 1990, 27 (05) :573-574

[8] RESPONSE CRITERIA FOR PHASE-II STUDIES OF SUPRATENTORIAL MALIGNANT GLIOMA [J].

MACDONALD, DR ;

CASCINO, TL ;

SCHOLD, SC ;

CAIRNCROSS, JG .

JOURNAL OF CLINICAL ONCOLOGY, 1990, 8 (07) :1277-1280