Specification of chemosensory neuron subtype identities in Caenorhabditis elegans

被引：25

作者：

Lanjuin, A ^{[1
]}

Sengupta, P ^{[1
]}

机构：

[1] Brandeis Univ, Dept Biol, Waltham, MA 02454 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2004年 / 14卷 / 01期

关键词：

D O I：

10.1016/j.conb.2004.01.006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cellular diversity in the nervous system arises from the presence of multiple neuronal subtypes, each of which is specialized to perform a unique function. Work in Caenorhabditis elegans has begun to reveal the pathways that are essential for the specification of identities of neuronal subtypes in its chemosensory system. The functions of each chemosensory neuron subtype are specified by distinct developmental cascades, using molecules from well-conserved transcription factor families. Additional cellular complexity is generated by novel mechanisms that further diversify the identities of the left and right members of a bilateral sensory neuron pair.

引用

页码：22 / 30

页数：9

共 64 条

[1] Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code [J].