Phenolic compounds from Gastrodia rhizome and relaxant effects of related compounds on isolated smooth muscle preparation

被引：95

作者：

Hayashi, J

Sekine, T

Deguchi, S

Lin, Q

Horie, S

Tsuchiya, S

Yano, S

Watanabe, K

Ikegami, F

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

[2] Yunnan Inst Tradit Chinese Med & Mat Med, Kunming, Yunnan, Peoples R China

来源：

PHYTOCHEMISTRY | 2002年 / 59卷 / 05期

关键词：

Gastrodia rhizome; Gastrodia elata; Orchidaceae; gastrol; phenolic compound; smooth muscle relaxant effect; postsynaptic nerve;

D O I：

10.1016/S0031-9422(02)00008-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gastrol (1), together with 10 known phenolic compounds. has been isolated from the MeOH extract of the rhizomes of Gastrodia elata Blume (Orchidaceae). and their structures were elucidated by detailed spectral analyses including by 2D NMR spectroscopic analyses. The relaxant effects of these constituents on smooth muscle preparations isolated from guinea-pig ileum were also studied in order to reveal their characteristic pharmacological activities. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：513 / 519

页数：7

共 14 条

[1] Neural emergency system in the stomach [J].