Calcium channelopathies in the central nervous system

被引：54

作者：

Jen, J ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Neurol, Los Angeles, CA 90095 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1999年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0959-4388(99)80040-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The recent discovery that familial hemiplegic migraine, episodic ataxia type 2, and spinocerebellar ataxia type 6 are allelic disorders caused by different mutations in CACNA1A, a calcium-channel-encoding gene, adds to a growing list of channelopathies causing paroxysmal neurologic disturbance and progressive neurodegeneration. Calcium channelopathies in the central nervous system provide a model to study the important roles that calcium channels play in neuronal function.

引用

页码：274 / 280

页数：7

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