Current status and progress of pancreatic cancer in China

被引:484
作者
Lin, Quan-Jun [1 ]
Yang, Feng [1 ]
Jin, Chen [1 ]
Fu, De-Liang [1 ]
机构
[1] Fudan Univ, Huashan Hosp, Shanghai Med Coll, Pancreat Dis Inst,Dept Pancreat Surg, Shanghai 200040, Peoples R China
关键词
Pancreatic cancer; Incidence; Diagnosis; Treatment; PHASE-III TRIAL; BODY-MASS INDEX; DIABETES-MELLITUS; DISTAL PANCREATECTOMY; CIGARETTE-SMOKING; PLUS GEMCITABINE; INCREASED RISK; RETROSPECTIVE COHORT; EARLY-DIAGNOSIS; SURVIVAL;
D O I
10.3748/wjg.v21.i26.7988
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pancreatic cancer incidence is more significant in the rural areas than in the urban areas. Annual diagnoses and deaths of pancreatic cancer in China are now beyond the number of cases in the United States. GLOBOCAN 2012 estimates that cases in China account for 19.45% (65727/337872) of all newly diagnosed pancreatic cancer and 19.27% (63662/330391) of all deaths from pancreatic cancer worldwide. The population's growing socioeconomic status contributes to the rapid increase of China's proportional contribution to global rates. Here, we present an overview of control programs for pancreatic cancer in China focusing on prevention, early diagnosis and treatment. In addition, we describe key epidemiological, demographic, and socioeconomic differences between China and developed countries. Facts including no nationwide screening program for pancreatic cancer, delay in early detection resulting in a late stage at presentation, lack of awareness of pancreatic cancer in the Chinese population, and low investment compared with other cancer types by government have led to backwardness in China's pancreatic cancer diagnosis and treatment. Finally, we suggest measures to improve health outcomes of pancreatic cancer patients in China.
引用
收藏
页码:7988 / 8003
页数:16
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