The role of cell adhesion molecules in synaptic plasticity and memory

被引:147
作者
Murase, S [1 ]
Schuman, EM [1 ]
机构
[1] CALTECH, Div Biol, Howard Hughes Med Inst, Pasadena, CA 91125 USA
关键词
D O I
10.1016/S0955-0674(99)00019-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Studies in the past few years suggest that cell adhesion molecules may play signaling as well as structural roles at adult synapses during plasticity. The observation that many adhesion molecules are expressed both pre-synaptically and postsynaptically raises the possibility that information about synaptic activity might simultaneously be communicated to both sides of the synapse, circumventing the need for distinct anterograde and retrograde messengers.
引用
收藏
页码:549 / 553
页数:5
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