Not paralysis, but dystonia causes stridor in multiple system atrophy

被引:82
作者
Merlo, IM
Occhini, A
Pacchetti, C
Alfonsi, E
机构
[1] Univ Pavia, Spinal & Cranial Reflexes Lab, Ist Neurol C Mondino, IRCCS, I-27100 Pavia, Italy
[2] Univ Pavia, Movement Disorders & Parkinsons Dis Unit, Ist Neurol C Mondino, IRCCS, I-27100 Pavia, Italy
[3] Univ Pavia, Dept Otorhinolaryngol, Policlin San Matteo, IRCCS, I-27100 Pavia, Italy
关键词
D O I
10.1212/WNL.58.4.649
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Electromyography (EMG) was performed in 10 patients with multiple system atrophy, laryngeal or pharyngeal symptoms, or both. In patients with stridor, EMG during quiet breathing revealed persistent tonic activity both abductor and adductor vocal cord muscles. In patients with dysphagia, the cricopharyngeal muscle showed persistent EMG activity throughout all phases of swallowing. Botulinum toxin injection into the adductor muscle determined subjective improvement and reduced tonic EMG activity. Therefore, the cause of stridor in multiple system atrophy is dystonia of the vocal cords.
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页码:649 / 652
页数:4
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