Management of the elderly patient with advanced non-small cell lung cancer

被引：16

作者：

Cheong, KA ^{[1
]}

Chrystal, K ^{[1
]}

Harper, PG ^{[1
]}

机构：

[1] Guys Hosp, Dept Med Oncol, London SE1 9RT, England

来源：

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | 2006年 / 60卷 / 03期

关键词：

NSCLC; elderly; chemotheraphy;

D O I：

10.1111/j.1368-5031.2005.00795.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Non-small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It is predominantly a disease of the elderly with the median age at diagnosis 68 years. Unfortunately, the majority of patients present with advanced disease whereby palliation is the primary aim of treatment. The elderly have a long history of undertreatment and non-inclusion in clinical trials with regard to cancer. Elderly-specific studies demonstrate that chemotherapy provides both a survival and quality-of-life benefit in advanced. NSCLC. Increasing emphasis is placed on the objective assessment of fitness for chemotherapy and the integration of molecularly targeted agents into treatment paradigms.

引用

收藏

页码：340 / 343

页数：4

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