Responsive polymers in controlled drug delivery

被引：1083

作者：

Bajpai, A. K. ^{[1
]}

Shukla, Sandeep K. ^{[1
]}

Bhanu, Smitha ^{[1
]}

Kankane, Sanjana ^{[1
]}

机构：

[1] Govt Autonomous Sci Coll, Dept Chem, Bose Mem Res Lab, Jabalpur 482001, MP, India

来源：

PROGRESS IN POLYMER SCIENCE | 2008年 / 33卷 / 11期

关键词：

Responsive polymers; Hydrogels; Drug delivery;

D O I：

10.1016/j.progpolymsci.2008.07.005

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

This article reviews the state-of-the art in responsive polymer systems for controlled drug delivery applications. The paper describes different types of stimuli-sensitive systems and gives an account of their synthesis through methods such as group transfer polymerization, atom transfer radical polymerization and reversible addition-fragmentation chain transfer polymerization. The article also discusses classification of various drug delivery systems: diffusion controlled systems, chemically controlled systems, swelling-controlled systems and modulated release systems. A survey of the recent literature on various stimuli-responsive polymer hydrogels in controlled drug delivery is also included. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1088 / 1118

页数：31

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