Statistical analysis plan for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2): a large-scale investigation to solve longstanding controversy over the most appropriate management of elevated blood pressure in the hyperacute phase of intracerebral hemorrhage

被引：7

作者：

Anderson, Craig ^{[1
,2
]}

Heeley, Emma ^{[1
]}

Heritier, Stephane ^{[1
]}

Arima, Hisatomi ^{[1
]}

Woodward, Mark ^{[1
]}

Lindley, Richard ^{[1
]}

Neal, Bruce ^{[1
]}

Huang, Yining ^{[3
]}

Wang, Ji-Guang ^{[4
]}

Parsons, Mark ^{[5
]}

Stapf, Christian ^{[6
]}

Robinson, Tom ^{[7
]}

Lavados, Pablo ^{[8
]}

Delcourt, Candice ^{[1
,2
]}

Davis, Stephen ^{[9
]}

Chalmers, John ^{[1
]}

机构：

[1] Univ Sydney, George Inst Global Hlth, Sydney, NSW 2006, Australia

[2] Royal Prince Alfred Hosp, Dept Neurol, Sydney, NSW, Australia

[3] Peking Univ, Hosp 1, Dept Neurol, Beijing 100871, Peoples R China

[4] Shanghai Jiao Tong Univ, Ruijin Hosp, Shanghai Inst Hypertens, Shanghai 200030, Peoples R China

[5] Univ Newcastle, John Hunter Hosp, Dept Neurol, Newcastle, NSW 2300, Australia

[6] Univ Paris 07, Hop Lariboisiere, Serv Neurol, Paris, France

[7] Univ Leicester, Leicester Royal Infirm, Dept Cardiovasc Sci, Leicester, Leics, England

[8] Univ Desarrollo, Dept Med, Clin Alemana, Serv Neurol, Santiago, Chile

[9] Univ Melbourne, Melbourne Brain Ctr, Melbourne, Vic, Australia

来源：

INTERNATIONAL JOURNAL OF STROKE | 2013年 / 8卷 / 05期

基金：

英国医学研究理事会;

关键词：

clinical trial; hypertension; intracerebral hemorrhage; methodology; stroke; HEMATOMA GROWTH;

D O I：

10.1111/ijs.12004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The Statistical analysis plan (SAP) for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2).

引用

页码：327 / 328

页数：2

共 8 条

[1] Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial
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Huang, Yining
Wang, Ji Guang
Arima, Hisatomi
Neal, Bruce
Peng, Bin
Heeley, Emma
Skulina, Christian
Parsons, Mark W.
Kim, Jong Sung
Tao, Qing Ling
Li, Yue Chun
Jiang, Jian Dong
Tai, Li Wen
Zhang, Jin Li
Xu, En
Cheng, Yan
Heritier, Stephan
Morgenstern, Lewis B.
Chalmers, John
[J]. LANCET NEUROLOGY, 2008, 7 (05) : 391 - 399
[2] Earlier Blood Pressure-Lowering and Greater Attenuation of Hematoma Growth in Acute Intracerebral Hemorrhage INTERACT Pilot Phase
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Wang, Ji Guang
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Neal, Bruce
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Anderson, Craig
[J]. STROKE, 2012, 43 (08) : 2236 - U429
[3] Lower Treatment Blood Pressure Is Associated With Greatest Reduction in Hematoma Growth After Acute Intracerebral Hemorrhage
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[4] Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage
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[5] The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2)
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Huang, Y.
Wang, J.
Heeley, E.
Lindley, R.
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[J]. INTERNATIONAL JOURNAL OF STROKE, 2010, 5 (02) : 110 - 116
[6] Hematoma growth and outcomes in intracerebral hemorrhage The INTERACT1 study
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[J]. NEUROLOGY, 2012, 79 (04) : 314 - 319
[7] Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (20) : 2127 - 2137
[8] Medical progress: Spontaneous intracerebral hemorrhage.
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Batjer, HH
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (19) : 1450 - 1460

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