Halymecins, new antimicrobial substances produced by fungi isolated from marine algae

被引：45

作者：

Chen, CY

Imamura, N

Nishijima, M

Adachi, K

Sakai, M

Sano, H

机构：

[1] Marine Biotechnology Institute, Shimizu Laboratories, Shimizu, Shizuoka 424

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 10期

关键词：

D O I：

10.7164/antibiotics.49.998

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Novel antimicroalgal substances halymecins A (1), B (2) and C (3) were isolated from the fermentation broth of a Fusarium sp. and halymecins D (4) and E (5) from an Acremonium sp. The structures of these halymecins, Fig. 1, were determined based on extensive D NMR studies as well as mass spectral data. These chemical structures are conjugates of di- and trihydroxydecanoic acid. Halymecin A showed antimicroalgal activity against Skeletonema costatum.

引用

页码：998 / 1005

页数：8

共 6 条

[1]

FAULKNER DJ, 1995, NAT PROD REP, V2, P75

[2]

HANNAFORD AJ, 1967, CARBOHYD RES, V3, P295

[3] NOVEL ANTIMYCIN ANTIBIOTICS, URAUCHIMYCIN-A AND URAUCHIMYCIN-B, PRODUCED BY MARINE ACTINOMYCETE [J].