Membrane anchors for vacuolar targeting: application in plant bioreactors

被引：21

作者：

Jiang, LW ^{[1
]}

Sun, SSM ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Biol, Hong Kong, Hong Kong, Peoples R China

来源：

TRENDS IN BIOTECHNOLOGY | 2002年 / 20卷 / 03期

关键词：

D O I：

10.1016/S0167-7799(02)01882-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Transgenic plants are attractive expression systems for producing recombinant proteins. Plant cells compartmentalize and store metabolites and proteins in vacuoles, but foreign proteins need to be targeted to the correct compartments if they are to accumulate in a stable fashion. Here we present a general strategy in which unique transmembrane and cytoplasmic tail sequences are used as anchors for delivering recombinant proteins via distinct vesicular transport pathways to specific vacuolar compartments where stable accumulation can occur.

引用

页码：99 / 102

页数：4

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