Bioconversion of substituted naphthalenes to the corresponding 1,2-dihydroxy derivatives by Escherichia coli recombinant strains

被引：10

作者：

DiGennaro, P

Bestetti, G

Galli, E

Orsini, F

Pelizzoni, F

Sello, G

机构：

[1] UNIV MILAN, DIPARTIMENTO GENET & BIOL MICRORGANISMI, I-20133 MILAN, ITALY

[2] UNIV MILAN, DIPARTIMENTO CHIM ORGAN & IND, I-20133 MILAN, ITALY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(97)01404-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,2-dihydroxynaphthalenes are produced by bioconversion of the corresponding hydrocarbons using Escherichia coli recombinant strains containing the naphthalene dioxygenase and dehydrogenase genes cloned from Pseudomonas fluorescens N3. Conversions are lead by a two step procedure without isolation of the dihydrodiol intermediate. Conversion rates depend on the position and nature of the naphthalene substituent (C) 1997 Elsevier Science Ltd.

引用

页码：6267 / 6270

页数：4

共 14 条

[1]

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[2]

Bestetti G, 1995, APPL MICROBIOL BIOT, V44, P306, DOI 10.1007/BF00169921

[3]

Bianchi D, 1995, EFCE PUBL S, P455

[4] A RAPID METHOD FOR NAPHTHALENE DIOXYGENASE ASSAY IN WHOLE CELLS OF NAPHTHALENE CIS-DIHYDRODIOL DEHYDROGENASE BLOCKED PSEUDOMONAS-FLUORESCENS - SCREENING OF POTENTIAL INDUCERS OF DIOXYGENASE ACTIVITY [J].