Cutaneous T-cell lymphoma in a 21-year-old male with Wolf-Hirschhorn syndrome

被引:6
作者
Batton, B
Amanullah, A
Main, C
Fivenson, D
Jamil, S
机构
[1] William Beaumont Hosp, Dept Pediat, Royal Oak, MI 48073 USA
[2] William Beaumont Hosp, Dept Hematol & Oncol, Royal Oak, MI 48073 USA
[3] Henry Ford Hlth Syst, Dept Dermatol, Detroit, MI USA
关键词
Wolf-Hirschhorn syndrome; cutaneous T-cell lymphoma; chromosome; 4;
D O I
10.1002/ajmg.a.20608
中图分类号
Q3 [遗传学];
学科分类号
071007 [遗传学]; 090102 [作物遗传育种];
摘要
We describe a case of cutaneous T-cell lymphoma occurring in a 21-year-old male with Wolf-Hirschhorn syndrome (WHS) due to a chromosome 4p16.3 deletion. This is the first documented case report of malignancy occurring in an adult with WHS. We also review the literature regarding patients with WHS and the joint occurrence of malignancy and discuss genetic changes involving chromosome 4 which may have contributed to the genesis of our patient's lymphoma. (C) 2003 Wiley-Liss, Inc.
引用
收藏
页码:81 / 85
页数:5
相关论文
共 41 条
[1]
Tlag2, an N-methyl-N-nitrosourea susceptibility locus, maps to mouse chromosome 4 [J].
Angel, JM ;
Richie, ER .
MOLECULAR CARCINOGENESIS, 2002, 33 (02) :105-112
[2]
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines [J].
Angrand, PO ;
Apiou, F ;
Stewart, AF ;
Dutrillaux, B ;
Losson, R ;
Chambon, P .
GENOMICS, 2001, 74 (01) :79-88
[3]
THE FGF FAMILY OF GROWTH-FACTORS AND ONCOGENES [J].
BASILICO, C ;
MOSCATELLI, D .
ADVANCES IN CANCER RESEARCH, 1992, 59 :115-165
[4]
Battaglia A, 2001, Adv Pediatr, V48, P75
[5]
Battin RH, 2000, J ASTRONAUT SCI, V48, P127
[6]
CHESI M, 2001, BLOOD, V98, P1271
[7]
INCIDENCE OF CUTANEOUS T-CELL LYMPHOMA AND OTHER RARE SKIN CANCERS IN A DEFINED POPULATION [J].
CHUANG, TY ;
SU, WPD ;
MULLER, SA .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 23 (02) :254-256
[8]
Allelic loss and promoter hypermethylation of the p15INK4b gene features in mouse radiation-induced lymphoid -: but not myeloid -: leukaemias [J].
Cleary, HJ ;
Boulton, E ;
Plumb, M .
LEUKEMIA, 1999, 13 (12) :2049-2052
[9]
KARYOTYPE STUDIES OF CUTANEOUS T-CELL LYMPHOMA - EVIDENCE FOR CLONAL ORIGIN [J].
EDELSON, RL ;
BERGER, CL ;
RAAFAT, J ;
WARBURTON, D .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1979, 73 (06) :548-550
[10]
A PATIENT WITH WOLF-HIRSCHHORN-SYNDROME ORIGINATING FROM TRANSLOCATION-T(4-8)(P16.3-Q24.3)PAT [J].
ELRIFAI, W ;
LEISTI, J ;
KAHKONEN, M ;
PIETARINEN, A ;
ALTHERR, MR ;
KNUUTILA, S .
JOURNAL OF MEDICAL GENETICS, 1995, 32 (01) :65-67