Palladium mediated activation of C-F bonds in 2,4,6-trifluoropyrimidine: Synthesis and structure of palladium pyrimidyloxy and pyrimidinone derivatives

被引：23

作者：

Braun, T ^{[1
]}

Schorlemer, V ^{[1
]}

Neumann, B ^{[1
]}

Stammler, HG ^{[1
]}

机构：

[1] Univ Bielefeld, Fak Chem, D-33501 Bielefeld, Germany

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2006年 / 127卷 / 03期

关键词：

palladium; binuclear compounds; fluorinated heterocycles; C-F activation;

D O I：

10.1016/j.jfluchem.2005.12.025

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

[PdMe2(dcpm)] (1) reacts with 2,4,6-trifluoropyrimidine in the presence of water to give the palladium derivative [PdMe{4-C4N2F2H(=O)}(dcpm)] (2). When additional triethylamine is present complex [PdMe(2-OC4N2F2H)(dcpm)] (4) in addition to 2 is formed. Compound 2 converts slowly into the binuclear complex [Pd(4-C4N2F2H(=O)}(mu-dcpm]2 (5). The molecular structure of 5 was determined by X-ray crystallography. The palladium-palladium distance is 2.5898(3)angstrom. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：367 / 372

页数：6

共 54 条

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