Partner responses to sildenafil citrate (viagra) treatment of erectile dysfunction

被引:49
作者
Montorsi, F
Althof, SE
机构
[1] Univ Vita Salute San Raffaele, Dept Urol, I-20132 Milan, Italy
[2] Case Western Reserve Univ, Sch Med, Ctr Maritial & Sexual Hlth, Cleveland, OH USA
关键词
D O I
10.1016/j.urology.2003.11.018
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Objectives. To evaluate in a pooled analysis of multiple studies the perceptions of effectiveness and overall treatment satisfaction in the partners of patients who received sildenafil citrate for treatment of erectile dysfunction. Partner satisfaction with treatment of erectile dysfunction can have a substantial impact on the continuation of therapy. Methods. Each partner rated the man's erectile function and her own intercourse satisfaction by responding to three appropriately modified questions from the International Index of Erectile Function, assessing frequency of erections, ability to maintain erections, and satisfaction of intercourse in 14 double-blind placebo-controlled trials of sildenafil. Partner satisfaction with sildenafil treatment was evaluated using the Erectile Dysfunction Inventory of Treatment Satisfaction partner questionnaire in six of these trials. Results. Of 3634 patients enrolled in these 14 trials, the partners of 930 patients agreed to participate. The partners reported that men receiving sildenafil had significantly greater erection frequency and ability to maintain erections than men receiving placebo, irrespective of patient age. Partners of sildenafil-treated men also had more frequent intercourse satisfaction compared with partners of placebo-treated men (P < 0.0001). In both treatment groups, the partner and patient responses correlated highly (P < 0.0001). The correlation between patient and partner Erectile Dysfunction Inventory of Treatment Satisfaction index scores was 0.80 for placebo and 0.86 for sildenafil (P < 0.0001). Conclusions. Partner evaluations corroborated the patient assessments, with both indicating that treatment with sildenafil resulted in statistically significant improvement in erectile function and suggesting that partners were satisfied with sildenafil treatment for erectile dysfunction. (C) 2004 Elsevier Inc.
引用
收藏
页码:762 / 767
页数:6
相关论文
共 19 条
[1]
Althof S., 2000, NURSE PRACT, V25, P11
[2]
EDITS: Development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction [J].
Althof, SE ;
Corty, EW ;
Levine, SB ;
Levine, F ;
Burnett, AL ;
McVary, K ;
Stecher, V ;
Seftel, AD .
UROLOGY, 1999, 53 (04) :793-799
[3]
THROUGH THE EYES OF WOMEN - THE SEXUAL AND PSYCHOLOGICAL RESPONSES OF WOMEN TO THEIR PARTNERS TREATMENT WITH SELF-INJECTION OR EXTERNAL VACUUM THERAPY [J].
ALTHOF, SE ;
TURNER, LA ;
LEVINE, SB ;
BODNER, D ;
KURSH, ED ;
RESNICK, MI .
JOURNAL OF UROLOGY, 1992, 147 (04) :1024-1027
[4]
When an erection alone is not enough: biopsychosocial obstacles to lovemaking [J].
Althof, SE .
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2002, 14 (Suppl 1) :S99-S103
[5]
ALTHOF SE, 1989, J SEX MARITAL THER, V15, P121
[6]
Report of the international consensus development conference on female sexual dysfunction: Definitions and classifications [J].
Basson, R ;
Berman, J ;
Burnett, A ;
Derogatis, L ;
Ferguson, D ;
Fourcroy, J ;
Goldstein, I ;
Graziottin, A ;
Heiman, J ;
Laan, E ;
Leiblum, S ;
Padma-Nathan, H ;
Rosen, R ;
Segraves, K ;
Segraves, RT ;
Shabsigh, R ;
Sipski, M ;
Wagner, G ;
Whipple, B .
JOURNAL OF UROLOGY, 2000, 163 (03) :888-893
[7]
Vacuum erection device in spinal cord injured men: Patient and partner satisfaction [J].
Denil, J ;
Ohl, LA ;
Smythe, C .
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 1996, 77 (08) :750-753
[8]
Erectile dysfunction in a primary care setting:: results of an observational, no-control-group, prospective study with sildenafil under routine conditions of use [J].
Gil, A ;
Martínez, E ;
Oyagüez, I ;
Palacios, G ;
Rejas, J .
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2001, 13 (06) :338-347
[9]
Health outcomes variables important to patients in the treatment of erectile dysfunction [J].
Hanson-Divers, C ;
Jackson, SE ;
Lue, TF ;
Crawford, SY ;
Rosen, RC .
JOURNAL OF UROLOGY, 1998, 159 (05) :1541-1547
[10]
PATIENT SATISFACTION WITH PHARMACOLOGICAL ERECTION PROGRAM [J].
HOLLANDER, JB ;
GONZALEZ, J ;
NORMAN, T .
UROLOGY, 1992, 39 (05) :439-441