Iontophoresis: A non-invasive ocular drug delivery

被引：144

作者：

Eljarrat-Binstock, E ^{[1
]}

Domb, AJ ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Fac Med, Sch Pharm, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel

来源：

JOURNAL OF CONTROLLED RELEASE | 2006年 / 110卷 / 03期

关键词：

iontophoresis; eye; hydrogel; ocular delivery;

D O I：

10.1016/j.jconrel.2005.09.049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iontophoresis as a non-invasive technique for ocular drug delivery has been investigated for many years. This paper provides an over-view of the approaches currently used in the development of the ocular iontophoretic device, the essential features of this procedure and the reported toxicity. This review focuses on the experimental results after transcorneal and transscleral iontophoresis of different drugs, emphasizing the current density applied and the treatment duration used by the investigators. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：479 / 489

页数：11

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