Medication-associated lesions of the GI tract

被引:29
作者
Seminerio, Jennifer [1 ]
McGrath, Kevin [1 ]
Arnold, Christina A. [2 ]
Voltaggio, Lysandra [3 ]
Singhi, Aatur D. [4 ]
机构
[1] Univ Pittsburgh Med Ctr, Dept Med, Pittsburgh, PA USA
[2] Ohio State Univ Wexner Med Ctr, Dept Pathol, Columbus, OH USA
[3] George Washington Univ, Dept Pathol, Washington, DC USA
[4] Univ Pittsburgh Med Ctr, Dept Pathol, Pittsburgh, PA USA
关键词
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; UPPER GASTROINTESTINAL-TRACT; LARGE-INTESTINE TRANSIT; ULCERATIVE-COLITIS; DIAPHRAGM DISEASE; SLOUGHING ESOPHAGITIS; PATHOLOGICAL OVERLAP; VASCULAR HAMARTOMA; ISCHEMIC COLITIS; MELANOSIS COLI;
D O I
10.1016/j.gie.2013.08.027
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Medications play an integral role in the health and wellbeing of patients. However, a large number of medications are reported to damage one or more segments of the GI tract, either directly or indirectly, resulting in a variety of clinicopathologic findings. Although some findings are pathognomonic for specific drugs, many more demonstrate nonspecific pathology. Early recognition of GI tract drug-induced injury is critical because the consequences of prolonged use, in some instances, can be fatal. Reducing the incidence of adverse effects requires an appropriate index of suspicion and good communication between the gastroenterologist and pathologist, both of which can significantly impact patient care. Copyright © 2014 by the American Society for Gastrointestinal Endoscopy.
引用
收藏
页码:140 / 150
页数:11
相关论文
共 70 条
[1]
Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol - Clinical, endoscopic, and histopathologic findings [J].
Abraham, SC ;
Bhagavan, BS ;
Lee, LA ;
Rashid, A ;
Wu, TT .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2001, 25 (05) :637-644
[2]
Erosive injury to the upper gastrointestinal tract in patients receiving iron medication - An underrecognized entity [J].
Abraham, SC ;
Yardley, JH ;
Wu, TT .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1999, 23 (10) :1241-1247
[3]
Abraham SC, 1999, MODERN PATHOL, V12, P1152
[4]
Bevacizumab and postponed suture leakages after surgery for ulcerative colitis and rectal cancer [J].
Adenis, Antoine ;
Vanseymortier, Luc ;
Foissey, David ;
Colombel, Jean-Frederic .
GUT, 2007, 56 (05) :734-734
[5]
Severe Ulcerative Colitis After Rituximab Therapy [J].
Ardelean, Daniela S. ;
Gonska, Tanja ;
Wires, Shannon ;
Cutz, Ernest ;
Griffiths, Anne ;
Harvey, Elizabeth ;
Tse, Shirley M. L. ;
Benseler, Susanne M. .
PEDIATRICS, 2010, 126 (01) :E243-E246
[6]
Arnold CA, 2013, MODERN PATHOL, V26, p144A
[7]
MELANOSIS OF THE RECTUM IN PATIENTS WITH CHRONIC CONSTIPATION [J].
BADIALI, D ;
MARCHEGGIANO, A ;
PALLONE, F ;
PAOLUZI, P ;
BAUSANO, G ;
IANNONI, C ;
MATERIA, E ;
ANZINI, F ;
CORAZZIARI, E .
DISEASES OF THE COLON & RECTUM, 1985, 28 (04) :241-245
[8]
BIGGAR WD, 1985, AM J PATHOL, V119, P5
[9]
Drug-induced esophageal damage: diseases of medical progress [J].
Boyce, HW .
GASTROINTESTINAL ENDOSCOPY, 1998, 47 (06) :547-550
[10]
Colonic toxicity of administered drugs and chemicals [J].
Cappell, MS .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (06) :1175-1190