Solid-phase syntheses of furopyridine and furoquinoline systems

被引：28

作者：

Cironi, P

Tulla-Puche, J

Barany, G

Albericio, F

Alvarez, M

机构：

[1] Univ Barcelona, Biomed Res Inst, E-08028 Barcelona, Spain

[2] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain

[3] Univ Barcelona, Dept Organ Chem, E-08028 Barcelona, Spain

[4] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 09期

关键词：

D O I：

10.1021/ol049762f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of 2-substituted furo[3,2-b]pyridines and furo[3,2-h]quinolines have been achieved for the first time in the solid-phase mode. The central enabling steps involved concomitant deprotection/cyclization promoted by the mild base K2CO3. Reactions were monitored "in situ" in real time by a variety of spectroscopic techniques, which allowed full and accurate control of progress in these syntheses.

引用

页码：1405 / 1408

页数：4

共 34 条

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