Enfurvitide prevents vertical transmission of multidrug-resistant HIV-1 in pregnancy but does not cross the placenta

被引：23

作者：

Brennan-Benson, P ^{[1
]}

Pakianathan, M

Rice, P

Bonora, S

Chakraborty, R

Sharland, M

Hay, P

机构：

[1] Univ London St Georges Hosp, Dept Genitourinary Med, London, England

[2] Univ London St Georges Hosp, Dept Virol, London, England

[3] Univ London St Georges Hosp, Paediat Infect Dis Unit, London, England

[4] Univ Turin, Dept Infect Dis, Turin, Italy

来源：

AIDS | 2006年 / 20卷 / 02期

关键词：

D O I：

10.1097/01.aids.0000200535.02232.1b

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The use of previously successful antiretroviral regimens in mother-to-child transmission (MTCT) prevention will be increasingly challenged by the rising prevalence of multidrug-resistant (MDR) HIV. We used enfurvitide together with an optimized antiretroviral backbone to prevent the MTCT prevention of MDR HIV in two pregnant women. The measurement of maternal and foetal peripheral blood levels of enfurvitide showed no evidence of transplacental transfer.

引用

页码：297 / 299

页数：3

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