Neurodevelopment on route p63

被引：9

作者：

Nicotera, P ^{[1
]}

Melino, G ^{[1
]}

机构：

[1] Univ Leicester, MRC, Toxicol Unit, Leicester LE1 9HN, Leics, England

来源：

NEURON | 2005年 / 48卷 / 05期

关键词：

D O I：

10.1016/j.neuron.2005.11.023

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

All known members of the p53 gene family, including the two homologs p73 and p63, have multiple biological functions. In neurons, p53 and p73 are known to regulate cell death in the developing and adult nervous system. A report by Jacobs et al. in this issue of Neuron shows that the more ancestral member of this gene family, p63, is an essential proapoptotic protein during neuronal development.

引用

页码：707 / 709

页数：3

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