A gut-heart connection in cardiometabolic regulation

被引：22

作者：

Buglioni, Alessia ^{[1
]}

Burnett, John C., Jr. ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, Cardiorenal Res Lab, Rochester, MN 55905 USA

来源：

NATURE MEDICINE | 2013年 / 19卷 / 05期

关键词：

ATRIAL-NATRIURETIC-PEPTIDE; HUMAN ADIPOCYTES; BLOOD-PRESSURE;

D O I：

10.1038/nm.3196

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new study establishes a link between glucagon-like peptide-1 (GLP-1) release from the gut and the cardiac hormone atrial natriuretic peptide, which lowers blood pressure. As GLP-1 receptor agonists are used to control glycemia in patients with type 2 diabetes, this new gut-heart axis suggests a role of these agents in overall cardiovascular homeostasis (pages 567–575).

引用

页码：534 / 536

页数：3

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