A voxel-by-voxel parametric fMRI study of motor mental rotation: hemispheric specialization and gender differences in neural processing efficiency

被引：26

作者：

Christova, Peka S. ^{[1
,2
]}

Lewis, Scott M. ^{[2
,3
]}

Tagaris, Georgios A. ^{[1
,2
,4
]}

Ugurbil, Kamil ^{[5
]}

Georgopoulos, Apostolos P. ^{[1
,2
,3
,6
,7
]}

机构：

[1] Univ Minnesota, Sch Med, Dept Neurosci, Minneapolis, MN 55455 USA

[2] Vet Affairs Med Ctr, Brain Sci Ctr, Minneapolis, MN 55417 USA

[3] Univ Minnesota, Sch Med, Dept Neurol, Minneapolis, MN 55455 USA

[4] Gen Athens Hosp, Dept Neurol, Athens, Greece

[5] Univ Minnesota, Sch Med, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USA

[6] Univ Minnesota, Sch Med, Dept Psychiat, Minneapolis, MN 55455 USA

[7] Univ Minnesota, Sch Med, Ctr Cognit Sci, Minneapolis, MN 55455 USA

来源：

EXPERIMENTAL BRAIN RESEARCH | 2008年 / 189卷 / 01期

关键词：

mental rotation; fMRI; gender; cerebral cortex;

D O I：

10.1007/s00221-008-1405-x

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Differences between men and women in brain size, cognitive performance and lateralization of brain activation have been perennial and controversial issues. Here we show that in a motor mental rotation task where women and men performed equally well, the slope of the functional magnetic resonance imaging (fMRI) blood oxygenation level dependent (BOLD) signal per degree of mental rotation was overall 2.4x higher in men than in women. This was attributed to the much more inefficient engagement (i.e. higher slopes) of the right hemisphere by men (mainly the frontal lobe). These findings indicate that women process information much more efficiently than men, which could offset smaller brain size.

引用

页码：79 / 90

页数：12

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