Regulation and characterization of the Na+/H+ exchanger

被引：12

作者：

Fliegel, L ^{[1
]}

Murtazina, R ^{[1
]}

Dibrov, P ^{[1
]}

Harris, C ^{[1
]}

Moor, A ^{[1
]}

Fernandez-Rachubinski, FA ^{[1
]}

机构：

[1] Univ Alberta, Dept Biochem, Edmonton, AB T6G 2H7, Canada

来源：

BIOCHEMISTRY AND CELL BIOLOGY | 1998年 / 76卷 / 05期

关键词：

cation translocation; intracellular pH; membrane protein; Na+/H+ antiporter; protein phosphorylation; protein-protein interaction;

D O I：

10.1139/bcb-76-5-735

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Na+/H+ exchanger is a ubiquitous protein present in all mammalian cell types that functions to remove one intracellular H+ for one extracellular Na+. Several isoforms of the protein exist, which are referred to as NHE1 to NHE6 (for Na+/H+ exchanger one through six). The NHE1 protein was the first isoform cloned and studied in a variety of systems. This review summarizes recent papers on this protein, particularly those that have examined regulation of the protein and its expression and activity.

引用

页码：735 / 741

页数：7

共 81 条

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