Organelles on the move: insights from yeast vacuole inheritance

被引:103
作者
Weisman, LS [1 ]
机构
[1] Univ Michigan, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrm1892
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Organelle inheritance is one of several processes that occur during cell division. Recent studies on yeast vacuole inheritance have indicated rules that probably apply to most organelle-inheritance pathways. They have uncovered a molecular mechanism for membrane-cargo transport that is partially conserved from yeast to humans. They have also shown that the transport complex, which is composed of a molecular motor and its receptor, regulates the destination and timing of vacuole movement and might coordinate organelle movement with several other organelle functions.
引用
收藏
页码:243 / 252
页数:10
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