Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

被引：35

作者：

Kamano, Y ^{[1
]}

Kotake, A

Hashima, H

Hayakawa, I

Hiraide, H

Zhang, HP

Kizu, H

Komiyama, K

Hayashi, M

Pettit, GR

机构：

[1] Kanagawa Univ, Fac Sci, Hiratsuka, Kanagawa 2591293, Japan

[2] Hokuriku Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 92011, Japan

[3] Kitasato Inst, Minato Ku, Tokyo 1088642, Japan

[4] Arizona State Univ, Canc Res Inst, Tempe, AZ 85287 USA

[5] Arizona State Univ, Dept Chem, Tempe, AZ 85287 USA

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1999年 / 64卷 / 07期

关键词：

marine natural products; bryozoa; Amathia convoluta; (2-phenylethyl)amine alkaloids; 3-hydroxyindol-2(3H)-one; convolutamine F; convolutamine G; convolutamydine E; cytostatic activity; isolation;

D O I：

10.1135/cccc19991147

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxyoxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

引用

页码：1147 / 1153

页数：7

共 5 条

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