A novel portable system for neonatal brain imaging

被引:8
作者
Chen, Y [1 ]
Zhou, SM [1 ]
Nioka, S [1 ]
Chance, B [1 ]
Delivoria-Papadopoulos, M [1 ]
Anday, E [1 ]
机构
[1] Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA
来源
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF | 1999年 / 3597卷
关键词
phased array; neonate; functional brain imaging;
D O I
10.1117/12.356817
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The possibility that a highly portable, fast, safe and affordable imaging system could obtain interpretable images of brain function in full- and pre-term neonates in a few seconds, has been explored in this paper. We have used a uniquely sensitive optical tomography system, termed phased array, which has revealed significant functional responses, particularly to parietal stimulation in normal and pathological states of neonate brain. This two-wavelength, frequency encoded phased array system can indicate the blood concentration and oxygenation change during the parietal brain activation in neonates. The preliminary clinical results are presented in this paper.
引用
收藏
页码:262 / 269
页数:8
相关论文
共 8 条
[1]   Precision localization of hidden absorbers in body tissues with phased-array optical systems [J].
Chance, B ;
Kang, KA ;
He, LB ;
Liu, HL ;
Zhou, SM .
REVIEW OF SCIENTIFIC INSTRUMENTS, 1996, 67 (12) :4324-4332
[2]   HIGHLY SENSITIVE OBJECT LOCATION IN TISSUE MODELS WITH LINEAR IN-PHASE AND ANTIPHASE MULTIELEMENT OPTICAL ARRAYS IN ONE AND 2 DIMENSIONS [J].
CHANCE, B ;
KANG, K ;
HE, L ;
WENG, J ;
SEVICK, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) :3423-3427
[3]  
CHANCE B, 1998, OSA
[4]  
CHANCE B, 1997, OSA
[5]  
NIOKA S, 1998, OSA
[6]  
NIOKA S, 1996, IN PRESS OXYGEN TRAN, V18
[7]  
OBRIG H, 1997, OPTICAL IMAGING BRAI, V2
[8]  
VILLRINGER A, 1997, TRENDS NEUROSCI, V20