Characterization of SLS parts for drug delivery devices

被引:75
作者
Low, KH [1 ]
Leong, KF [1 ]
Chua, CK [1 ]
Du, ZH [1 ]
Cheah, CM [1 ]
机构
[1] Nanyang Technol Univ, Sch Mech & Prod Engn, Ctr Design Res, Singapore, Singapore
关键词
lasers; scanning; drugs; delivery;
D O I
10.1108/13552540110410468
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
There are many applications for rapid prototyping systems and application in the biomedical field is an important domain. Uses selective laser sintering (SLS) in this study to build porous cylindrical disc matrices for use as drug delivery devices (DDD). Studies the part-bed temperature to ascertain its influence over the porosity of the disc matrices. They are found to have an inverse linear relationship. Also investigates the dense walls, the inherent consequences of building porous structures with the SLS, in the disc matrix as they have a direct impact on the performance of the DDD. Discusses the size constraint of the disc matrix due to the limitations of the SLS process. Also investigates the possibility of creating disc matrices of varying porosity. Experimental results demonstrate that SLS is viable in producing DDDs that have variable porosity and micro-features.
引用
收藏
页码:262 / 267
页数:6
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