Bovine pericardium versus homologous sclera as wrapping materials for hydroxyapatite ocular implants: An animal study

被引：26

作者：

DeBacker, CM ^{[1
]}

Dutton, JJ ^{[1
]}

Proia, AD ^{[1
]}

Holck, DEE ^{[1
]}

Stone, T ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Ctr Eye, Dept Ophthalmol, Durham, NC 27710 USA

来源：

OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY | 1999年 / 15卷 / 05期

关键词：

D O I：

10.1097/00002341-199909000-00003

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: We compared bovine pericardium and homologous sclera as wrapping materials for hydroxyapatite (HA) ocular implants in enucleated New Zealand white rabbits. Methods: Eighteen rabbits were unilaterally enucleated and the sockets implanted with IO-mm HA spherical implants. Six implants were wrapped with homologous sclera, 6 with bovine pericardium, and 6 were not wrapped. The rabbits were killed 7 weeks later and the sockets were examined clinically for inflammation and implant exposure. Exenterated specimens were assessed histopathologically for inflammation and vascularization. Results: No clinical evidence of implant exposure or extrusion was detected in rabbits receiving sclera or bovine pericardium wrapped implants. Histopathologically, the bovine pericardium displayed more inflammation in its outer portion, as well as more disruption of its lamellar arrangement than did the sclera. Fibrovascular ingrowth was complete in all wrapped implants. Conclusion: Bovine pericardium behaves similar clinically to homologous sclera as a wrapping material for spherical HA ocular implants in a rabbit model, and may represent a reasonable alternative to sclera in such procedures in humans.

引用

页码：312 / 316

页数：5

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